论文部分内容阅读
One of the challenges in the treatment of colorectal cancer patients is resistance to radiation treatment.MicroRNAs(miRNAs)are involved in essential biological activities,including chemoresistance and radioresistance.Several research studies have indicated that miRNAs played an important role in sensitizing cellular response to ionizing radiation(IR).In this study,we found that miR-124 is significantly down-regulated both in CRC-derived cell lines and clinical CRC samples compared with adjacent non-tumor colorectal tissues.