苏醒间术后烦躁患者应用右美托咪啶和丙泊酚比较性研究

来源 :中国中西医结合麻醉学会年会暨第二届全国中西医结合麻醉学术研讨会 | 被引量 : 0次 | 上传用户:zhang332974789
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  目的:观察在麻醉恢复室中全麻术后烦躁病人应用右美托咪啶的临床疗效,观察其用于术后烦躁病人的血流动力学的影响及安全性探讨.方法:选择择期全麻手术术后送入苏醒间RSS躁动评分≥2的患者50例,随机分为右美托咪啶组(D组)和丙泊酚组(P组)各25例.D组入PACU即可静脉缓慢输注右美托咪啶(由江苏恒瑞医药股份有限公司生产)0.5μg/kg,输注时间>10分钟;P组入PACU即可缓慢静推丙泊酚1mg/kg,注意观察生命指征.分别记录入PACU即刻(T1)及10min(T2)、20min(T3)时脉搏氧饱和度(SPO2)、平均动脉压(MAP)、心率(HR)、RSS评分和Ramsay评分.SPO2低于90给予面罩吸氧,心率低于50给予阿托品0.5mg.记录患者苏醒期恶心呕吐等不良反应的发生情况,苏醒程度采用Steward苏醒评分量表评估,量表满分为6分,5分以上方可离开苏醒间.
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