To investigate the role of c-Maf SUMOylation in T cells and its effect on the development of autoimm

来源 :第十二届中国实验动物科学年会 | 被引量 : 0次 | 上传用户：mmssbb

【摘要】

：

　　SUMOylation on c-Maf is reported to decrease its transcriptional activity for IL-4,a key cytokine which promotes the protective Th2 cells in non-obese diabe

【作者】

：

Chao-Yuan Hsu Huey-Kang Sytwu

【机构】

：

GraduateInstituteofLifeSciences;DepartmentandGraduateInstituteofMicrobiologyandImmunology;NationalDe

【出处】

：

第十二届中国实验动物科学年会

【发表日期】

：

2016年10期

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　　SUMOylation on c-Maf is reported to decrease its transcriptional activity for IL-4,a key cytokine which promotes the protective Th2 cells in non-obese diabetic (NOD) mice.However,the physiological significance of SUMO-modulated c-Maf in autoimmune diabetes is not completely understood.

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To investigate the role of c-Maf SUMOylation in T cells and its effect on the development of autoimm

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