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Wilsons disease is a genetic disorder causing excessive accumulation of copper in the body leading to toxic damage especially in the liver and in the nervous system.The current treatment is based on low-molecular weight copper chelators and zinc salts that have some burdensome side effects that arise as a consequence of absorption into the blood and organs after ingestion[1].We design new biomaterials based on cellulose and crosslinked chitosan with covalently bounded copper chelator as potential drugs for the treatment of Wilsons disease (Fig.1).