Translating neural control research into practice of stroke rehabilitation

来源 :中国神经科学学会第九届全国学术会议暨第五届会员代表大会 | 被引量 : 0次 | 上传用户:yuehungulei
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Motor rehabilitation for stroke patients is a process of relearning of motor programs that are either damaged or destroyed in the brain.Repeating of motor programs can be facilitated by external assistance provided to the neuromuscular system.Motor training in patients with an induced movement that mimics normal motor activities can be benefit recovery of motor functions.Furthermore, functional electrical stimulation (FES) has been proven to be effective for motor rehabilitation.We are using computational methods to understand neural control of movement in normal human, and are developing a hybrid FES robotic device to perform training of stroke patients.Normal patterns of neuromuscular activation during movement will be translated into control strategy for FES robotics.This presentation wilt review our recent work in stimulation of neural control and in the development of the hybrid FES robotic system.
其他文献
Objective Various highly conserved genes and proteins are expressed during embryonic development.Neuronal Development-Associated Protein (NDAP) is a newly identified protein which was cloned and ident
Myelin biogenesis is a complex process involving coordinated exocytosis, endocytosis, mRNA transport and cytoskeletal dynamics.While abnormalities of myelin are common in lysosomal storage diseases, o
会议
Somatosensory ganglia including dorsal root ganglion (DRG) and trigeminal ganglion (TG) are derived from a common pool of neural crest stem cells (NCCs), and are good systems to study the mechanisms o
Nkx2.2 homeodomain transcriptional factor is initially expressed in differentiating oligodendrocyte precursor cells (OPCs) and plays a critical role in regulating the differentiation process.Recent st
星形胶质细胞在疾病和损伤条件下对神经元的功能和完整性起着重要作用。目前已经明确星形胶质细胞上表达的谷氨酸转运体2 (GLT1)在阻止引起中枢神经系统内损伤引起的兴奋性中毒中起着重要作用,但是其表达和功能的分子调控机制还很不清楚。本课题研究insulin/Rheb/mTor通路是否以及如何调节GLT1在神经元一胶质细胞微环境中的表达和功能。我们发现短时间给予insulin或rapamycin都可以引
Brain blood vasculature consists of a highly ramified vessel network that is tailored for brain function.As the brain by itself does not produce vascular progenitor cells, ingression of blood vessels
会议
The dentate gyrus is one of the regions where neurons are continuously born throughout life.In adult, the mechanism of neurogenesis has attracted much attention over the past years; however, how the g
Neurotrophin-3 (NT-3), a member of neurotrophin family, exerts numerous functions in central nerves system regarding for its ability to induce intracellular calcium elevation, however, the identity of
Objective A collection of in vitro evidence has demonstrated that Notch signaling plays a key role in the growth of neurites in differentiated neurons.However, the effects of Notch signaling on axon o
Objective Canonical Wnt/β-catenin signals play important roles during neuronal differentiation and neurogenesis, but less is known about noncanonical Wnt signals in this context.Recently, increasing e