Different biomechanical properties of medial and adventitial layers of thoracic aorta in Wistar-Kyot

• 作 者: Wei-qing HAN Jing CHEN Ling-yun WU Ding-liang ZHU Ping-jin GAO
• 机 构: State Key Laboratory of Medical Genomics,Shanghai Key Laboratory of Vascular Biology and Department
• 出 处: The Fourth Shanghai International Conference on Biophysics a
• 发表日期: 2010年12期
• 关键词: thoracic aorta media adventitia elastic stiffness maximum stiffness spontaneousl

　　Aim: The detailed mechanical properties of various layer of large conduit artery are important for understanding the function of the vessels.Traditionally, the artery wall was viewed as homogenous in biochemical and biomechanical analysis.This study was aimed at evaluating the mechanical role of thoracic media and adventitia in load-strain response in 16-and 32-week-old normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR).