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Whether graphene and graphene oxide(GO)would affect the activities of bacteria,acting as either an antimicrobial agent,or a stimulator to enhance bacterial growth,has been under debate.Nevertheless,how graphene derivatives with biocompatible coatings interact with microorganisms and the underlying mechanisms remain to be further explored.Herein,three types of nano-GOs functionalized with polyethylene glycol(nGO-PEGs)were synthesized by varying the PEGylation degree,and their effects on Escherichia coli(E.coli)growth were carefully investigated.