The neuroprotective effects of baicalin on ethanol-induced impairment via anti-oxidative and anti-ap

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户:vbsunboy
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Baicalin is a major bioactive ingredient from the roots of Scutellaria baicalensis Georgi and has various pharmacological actions such as anti-apoptosis and anti-oxidative stress.However,an involvement of baicalin in the ethanol-induced cerebral impairment remains unknown.
其他文献
目的 寻找会阴切口感染的高危因素,为临床控制感染制定相应措施提供方法学依据.方法 采用病例对照研究1∶2配对分层设计,调查某院48例病例和96例对照共144份资料,应用条件logistic回归的方法对文化程度、基础疾病、BMI指数、阴道检查次数、留置导尿管、缝合方式、胎儿体重、出血量、预防抗生素、接产人员年资等23个项目进行回归分析.结果 外缝、留置导尿管的OR值分别为16.42、2.765为危险
目的 肺囊性纤维化(Cysticfibrosis CF)是多种原因造成的疾病,如何快速准确的做出药敏结果指导临床用药,延缓和减轻囊性纤维化的进程,解除患者的痛苦是临床微生物工作者亟待解决的问题。方法 纸片扩散法(KB法)。结果 真菌的分离率偏高,其中白假丝酵母菌的分离率占首位,对氟康唑、伊曲康唑耐药率呈逐年上升的趋势;革兰阴性杆菌的分离率呈逐年上升趋势,耐亚胺培南的大肠埃希菌、肺炎克雷伯菌也时有检
产气荚膜梭菌感染所致气性坏疽是一种迅速发展的广泛性肌肉坏死的严重性感染,通常发生于开放性骨折、深层肌肉广泛性挫伤等,感染严重者时需尽快截肢。本文从骨软骨瘤术后患者中先后分离出产气荚膜梭菌、金黄色葡萄球菌、大肠埃希菌三种菌,从病例、病原学检查、治疗等做了相关报道。
We have reported that acute administration of Dehydroepiandrosterone-sulfate(DHEAS) for 10 min induced a short-term potentiation(STP) in rat hippocampal slices via mGluR5 and ryanodine receptor(Xu et
Caveolin-1(Cav-1),as an important structural protein of caveolae,has been proved to be correlated with several signal transduction pathways.Recent studies showed that Cav-1 may play a critical role in
The purpose of our present work was to study the hemispheric features of fast EEG ripples.Experiments were performed on male KM mice,weighting 15-25g.Under the anaesthesia of 10 %(1g/kg) urethane (i.p
Sigma receptor (σR) is a unique receptor family,which includes two subtypes:σR1 and σR2.Activation of σR1 is involved in the modulation of a series of physiological processes in the central nervous sy
目的:观察去卵巢骨质疏松大鼠全骨髓细胞培养前后GSK-3β/β-catenin 信号通路的变化。方法:将18 只健康3 月龄未经产雌性SD 大鼠随机平分为去卵巢和假手术两个组。术后14 周,取左侧股骨,新鲜分离骨髓细胞,一部分直接提取蛋白;另一部分采用静置贴壁法体外培养9 天后,收集细胞提取蛋白。
As a kind of functional water-soluble fullerene derivative,fullerenol has driven extensive applications in biomedical fields.Fullerenol is known to protect cells and tissues as well as to have other p
目的:探讨中枢神经元型一氧化氮合酶(neuronal nitric oxide synthetase,nNOS)与烟碱型乙酰胆碱受体(nicotinic acetylcholine receptor,nAChR)共定位对Aβ 诱导的大鼠认知功能障碍的影响。方法:SD 大鼠60 只,随机分成6 组,分别经侧脑室注射凝聚态Aβ 1-42(Aβ 组)或等量生理盐水(NS 组);以及经侧脑室注射Aβ 1-