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  5. Acid sphingomyelinase/ceramide regulates carotid intima-media thickness in hindlimb unloaded rats

Acid sphingomyelinase/ceramide regulates carotid intima-media thickness in hindlimb unloaded rats

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：bigsoul
【摘 要】
：
Weightlessness or simulated weightlessness would induce structural adaptation of arteries,but the effect of it on the carotid artery and the underlying mechanisms are still to be elucidated.In the pre
【作 者】
：
Yao-Ping Cheng Hai-Jun Zhang Yu-Ting Su Xing-Xing Meng Xiao-Ping Xie Yao-Ming Chang Jun-Xiang Bao 
【机 构】
：
Department of Aerospace Hygiene,Fourth Military Medical University,Xi'an 710032,P.R.China
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
ceramide acid sphingomyelinase common carotid artery vascular remodeling intima- 
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　　Weightlessness or simulated weightlessness would induce structural adaptation of arteries,but the effect of it on the carotid artery and the underlying mechanisms are still to be elucidated.In the present study,we aimed to investigate the changes of common carotid artery intima-media thickness(CIMT)after simulated weightlessness and role of acid sphingomyelinase/ceramide(ASM/Cer)pathway in the regimen.4-wk hindlimb unloaded tail suspended(HU)rats were used to simulate the effect of weightlessness.
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