The positive expression of SET8 possesses prognostic relevance and mediates Wnt target gene activati

• 作 者: Tianyi Shen Xiaoming Yi Wenquan Zhou
• 机 构: Nanjing General Hospital of Nanjing Military Region, Nanjing 210002, China
• 出 处: 泌尿生殖肿瘤华夏医学论坛2016暨长城国际泌尿男科转化医学论坛2016
• 发表日期: 2016年8期
• 关键词: SET8 renal cell carcinoma (RCC) Wnt target

　　Background: Renal cell carcinoma (RCC) is common renal malignancy within poor prognosis.Histone methylase SET8 plays vital roles in tumorigenesis through regulating Wnt/ β-catenin signaling and other cancer-related pathways.