Human cytomegalovirus (hCMV) causes birth defects in newborns and severe infections in immunocompromised patients.Chronic CMV infection may also contribute to immunosenescence during aging.Anti-hCMV t
囊性纤维化跨膜转导调节因子(Cystic fibrosis transmembrane conductance regulator,CFTR)是上皮细胞膜上一种转导氯离子的离子通道,其基因突变可导致上皮细胞液体运输失调及囊性纤维化(Cystic Fibrosis,CF),引起呼吸系统疾病表现为肺部感染、肺组织纤维化、阻塞性肺疾病；消化系统疾病表现为急慢性胰腺炎、胰功能不全、胆汁性肝硬化；生殖系统疾
Objectives: Mesangial deposition of aberrantly glycosylated IgA1 (agIgA1) and its immune complex is an initial and key pathogenic mechanism in IgA nephropathy (IgAN).The present study tested the hypot
In the present study, we found that H3 receptor expression was upregulated after ischemia/reperfusion (I/R) both in transient middle cerebral artery occlusion and oxygen-glucose-deprivation/reperfusio
目的：本实验采用左冠状动脉结扎法制备小鼠心肌梗死模型,研究小鼠急性心肌梗死后不同肠段通透性的变化.方法：将C57BL/6小鼠随机分为假手术组(Sham组)和急性心肌梗死组(AMI组),每组18只.AMI组开胸结扎左冠状动脉前降支,Sham组只开胸过线不结扎,小鼠心脏行2,3,5-氯化三苯基四氮唑(TTC)染色确定小鼠是否有心肌梗死.术后第3天行小鼠超声评价小鼠的射血分数(EF)和短轴缩短率(FS)
Objective To detect the effect of myricanol on expression of tumor related genes in human hepatoma HepG2 cells.Methods Expression level of tumor related genes were detected by qRT-PCR and Western blot
AIM: Evidence shows that ischemic stroke can induce structural reorganization of brain white matter (WM) microstructure.Acupuncture is advised as an adjunct to mainstream rehabilitation after stroke.H
Objective: To study the effect of Arctigenin on human breast cancer cells in vitro and its possible influencing mechanism.Methods: MTS assay was used to measure the effect of different concentrations
Aim: This study was aimed at assessing the safety and efficacy of transplantation with allogeneic skin tumors to treat chemically induced skin tumors in mice.
A key barrier to the development of gene therapy remains the lack of safe, efficient and easily controllable vehicles for gene delivery.The fundamental problems associated with the viral vehicles, e.g