Elements are essential for a healthy body.Although studies have examined proteins and nucleic acids at the molecular level,the intracellular distribution of elements and their functions are not well u
An analytical platform based on asymmetric flow field flow fractionation(AF4)coupled on-line to light scattering(LS),UV or fluorescence(FL)spectroscopies and ICP-MS has proven useful in characterizati
When human hepatoma HepG2 cells were exposed to sodium selenite,an unknown selenium metabolite was detected in the cytosolic fraction by HPLC-inductively coupled plasma mass spectrometry(LC-ICP-MS).
The research of protein on a single-cell level would aid the studies of the role of cellular heterogeneity in disease progression.A few methods,such as flow cytometry,mass cytometry,have realized sing
With the advances in molecular biology,a wide use of cell lines is allowed for metal analysis,which provides more information of bioavailability,toxicity,cancerogenicity,and mutagenicity of metals to
Modern metallomics is an especially challenging analytical undertaking because it relies upon measurement of both atomic and molecular chemical information in order to inform complex chemical question
Laser ablation sampling technique combined with ICP-mass spectrometry(LAICPMS)has become one of the most sensitive and versatile analytical tool for elemental imaging for minerals,fossils or various b