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Metabolic syndrome (MetS) is a complex of metabolic abnormalities such as obesity, hyperglycemia, hyperlipidemia and elevated blood pressure.The results of some studies in humans and experimental animals indicate that soy protein foods may be effective in the prevention and treatment of MetS because of their ability to decrease blood lipids and glucose.In the study with crossover design we investigated the effects of two-month consumption of 30g/day of soy protein isolate (SPI) and skimmed curd protein on serum lipids in persons with hyperlipidemia and excessive body mass.