The relationship between nonalcoholic fatty liver and insulin resistance

• 作 者: MaLina;FengMing;ZhouYingzhi;MaJia;HaoPeng;
• 机 构: Xuanwu Hospital Capital University of Medical Science, Beijing 100053, China
• 出 处: 第三届全国病毒性肝炎慢性化重症化基础与临床研究进展学术会议
• 发表日期: 2013年期

　　Objective: To explore the relationship between nonalcoholic fatty liver and insulin resistance.Method: 102 patients were divided into two groups: NAFLD group(n=52) and without NAFLD group(n=50), BMI, WHR, TC, TG, CRP, HDL-C, LDL-C, ALT, Cr, FPG, FINS and HOMA-IR were compared between the two groups, and logistic regression was analyzed.Results: In NAFLD group, the level ofBMI(26.7±2.3 vs 22.4±2.5, P<0.01), WHR(0.94± 0.06 vs 0.83 ± 0.05, P<0.01), TG(2.4 + 0.6 vs 1.8 ± 0.6, P<0.01), ALT(37.3 ± 8.3 vs 28.1±7.2, P<0.05), FPG(6.2± 1.4 vs 5.2±0.7, P<0.01), FINS(23.6± 13.6 vs 8.6±3.5, P<0.01)、 HOMA-IR(6.7 ± 4.7 vs 2.0± 1.6, P<0.01) were higher than the control group.In the logistic regression BMI(P<0.01), WHR(P< 0.01), TG(P<0.01), ALT(P <0.05) and HOMA-IR (P<0.01) were independent factors.Conc l us ions: BMI, WHR, TG, ALT and HOMA-IR were independent factors of NAFLD.