• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. TIPE2 negatively regulates mycoplasma pneumonia-triggered immune response via MAPK signaling pathway

TIPE2 negatively regulates mycoplasma pneumonia-triggered immune response via MAPK signaling pathway

来源 :2017年第二届全国特殊病原体学术会议 | 被引量 : 0次 | 上传用户：WUST_SXC
【摘 要】
：
Objective Excessive immune responses played an important role in pathogenetic effects of mycoplasma pneumonia (MP) infection.Tumor necrosis factor-α-induced protein 8-like 2 (TIPE2) is a negative regu
【作 者】
：
Yuanyuan Zhang Yunlian Zhou Dehua Yang Zhimin Chen 
【机 构】
：
The Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310052,P.R.China
【出 处】
：
2017年第二届全国特殊病原体学术会议
【发表日期】
：
2017年4期
【关键词】
：
Mycoplasma pneumonia Tumor necrosis factor-α-induced protein 8-like 2 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Objective Excessive immune responses played an important role in pathogenetic effects of mycoplasma pneumonia (MP) infection.Tumor necrosis factor-α-induced protein 8-like 2 (TIPE2) is a negative regulator of immune response,and could prevent hyper-responsiveness and maintain immune homeostasis.
其他文献
丝状支原体丝状亚种的脂质相关膜蛋白通过NF-kB途径释放IL-1β的分子机制
目的 为了明确丝状支原体丝状亚种(Mycoplasma mycodis subsp mycodies Mmm)的lipid-associated membrane proteins (LAMPs)引起宿主细胞的释放IL-1β的分子机制,本研究以胎牛肺细胞(EBL)为细胞模型,针对调控细胞因子释放的NF-kB、MAPK信号通路及关键信号分子TLR2、MyD88、IRAK4,明确宿主细胞在感染MmmL
会议
Immunization with Chlamydia psittaci plasmid protein CPSIT_p7 induces protective immunity against ch
To evaluate the immune protective efficacy of Chlamydia psittaci plasmid protein CPSIT_p7 and to analyze the potential mechanisms.In the current study,recombinant CPSIT_p7 protein was used to vaccinat
会议
Chlamydia psittaciCPSIT_p7Protective immunityCD4+cells
Distribution of Chlamydia abortus in fetus originating from artificially infected pregnant ewes
Objective The aim of this study was to quantify chlamydial loads in foetal organs and find the implication between fetus infection and abortion by experimentally mimicking Chlamydia.abortus infection
会议
Chlamydia abortusPregnant ewesChlamydial load
CXCL13 chemokine as a promising biomarker to diagnose neurosyphilis in HIV-negative patients
Background Chemokine ligand 13 (CXCL13) is believed to play a role in the recruitment of B cells in the central nervous system during neuroinflammation.Neurosyphilis is a group of clinical syndromes o
会议
NeurosyphilisTreponema pallidumCXCL13Cerebrospinal fluidNeuroinflammation
预防猪鼻支原体感染细胞的多肽药物研发
目的 细胞培养中的支原体污染严重影响生命科学研究的实验结果,猪鼻支原体是污染细胞的最常见支原体类型,并与肿瘤的发生发展密切相关。本研究旨在阐明猪鼻支原体感染细胞的分子机制,并在此基础上研发抗猪鼻支原体感染的新型药物。方法 通过GST-Pulldown、蛋白质谱分析、激光共聚焦、抗体阻断、基因表达干扰、竞争抑制等不同方法鉴定猪鼻支原体与细胞的相互作用蛋白及区域；通过多肽合成与标记、PCR、ELISA
会议
猪鼻支原体感染预防药物多肽
重组SPLUNC1蛋白对感染MO的盘羊杂交羊治疗作用研究
目的 探究绵羊重组短鄂、肺及鼻咽上皮细胞克隆1 (Short palate,lung and nasal epithelium clone l,SPLUNCl)蛋白对感染绵羊肺炎支原体(Mycoplasma ovipneumoniae,MO)的盘羊杂交羊的治疗效果。方法 将6只巴什拜羊为A组,18只盘羊杂交羊每组6只随机分为B、C和D组,人工感染MO,C、D组感染后第5d开始,分别每天气管注射1次
会议
绵羊肺炎支原体SPLUNC1绵羊盘羊杂交羊
Notch信号通路在肺炎支原体肺炎炎症机制中的作用研究
目的 分析肺炎支原体肺炎(MPP)患儿外周血单个核细胞Notch配体的表达水平其临床意义。方法 选择2015年3月至2016年7月在苏州大学附属儿童医院住院治疗的85例MPP患儿作为研究对象，同时选择35例同期择期手术患儿作对照研究。采用荧光实时定量PCR(RT-PCR)检测其外周血单个核细胞Notch配体Jagged1、Jagged2、DLL1及DLL4的表达水平；采用酶联免疫吸附实验(ELIS
会议
肺炎支原体肺炎Notch信号通路外周血单个核细胞
Macrophage Migration Inhibitory Factor as a Novel Cerebrospinal Fluid Marker for Neurosyphilis among
Background Neurosyphilis (NS) is difficult to diagnose especially in syphilis patients with negative cerebrospinal fluid (CSF) Rapid Plasma Reagin (RPR) or Venereal Disease Research Laboratory (VDRL).
会议
Macrophage migration inhibitory factorTreponema pallidumNeurosyphilisDiagnosi
The timing of azithromycin treatment is not associated with the clinical prognosis of Mycoplasma pne
Background Mycoplasma pneumoniae infection is a major cause of community-acquired pneumonia in children.We performed a retrospective study to evaluate the timing of azithromycin treatment in children
会议
Mycoplasma pneumoniaeazithromycinclinical prognosis
Whole Genome Sequence of the Treponema pallidum subsp.pallidum Strain Amoy: An Asia Isolate Is Highl
Syphilis is the third leading epidemic diseases around the world and in China,affecting at least 25 million persons worldwide.T.pallidum ssp.pallidum is the known pathogen for syphilis;however,not all
会议
Treponema pallidumWhole genome sequence