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Objective To discuss the prevention and treatmentstatus of Retinopathy of Prematurity in Guangdong Province.Methods122 medical institutions was chosen from health services which has the ability to carry out neonatesadopting the method of stratified random sampling.A questionnaire has been used.122 medical institutionsincluded 50 three-level medical institutions,72 secondary and the subordinate medical institutions.The distributing and collecting of questionnaires were conducting by a training projector leader.Toverify uncertain questionnaires with the phone.Using SPSS software to have data statistical analysis after quality control,P-values less than 0.05 considered as statistically significant.