What does TREM2 tell us about the role of microglia and inflammation in Alzheimer's disease?

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：cd21love

【摘要】

：

Lack of a functional TREM2-DAP12 signaling pathway causes early onset cognitive dementia in humans evident by the third decade of life.More recently,a single heterozygous mutation in TREM2 was found t

【作者】

：

Monica J Carson Yoshinori Otani Deirdre S.Davis Slawomir Sloniowski Abdullah Madany Alfredo Hernandez Andrea Tenner Devin Binder Peter Hickmott Iryna M Ethell

【机构】

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University of California Riverside School of Medicine,Center for Glial-Neuronal Interactions

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

microglia TREM2 synapse dementia and inflammation

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What does TREM2 tell us about the role of microglia and inflammation in Alzheimer's disease?

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