A Novel Collaborative Assembly Strategy for Tumor-Targeted siRNA Delivery

• 作 者: QiongSun;RanMo;YunkaiShang;CanZhang;
• 机 构: Center of Drug Discovery and Department of Pharmaceutics,China Pharmaceutical University,Nanjing 210
• 出 处: 2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
• 发表日期: 2014年期

　　Development of safe and efficient small interfering RNA (siRNA) delivery systems still remains elusive in clinical applications of siRNA for cancer treatment.[1] An ideal siRNA delivery system is required to be stable in the blood for preferential tumor targeting and overcome a variety of physiological barriers followed by efficient intracellular siRNA release for enhanced therapeutic efficacy.