Extracellular Anterior Gradient-2 (AGR2) Protein Enhances TumorCell Proliferation and Migration Thro

• 作 者: ZHEQI Li DAWEI Li
• 机 构: School of Pharmacy, Shanghai Jiao Tong University
• 出 处: 中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议
• 发表日期: 2014年3期
• 关键词: Anterior Gradient-2 (AGR2) Insulin-like Growth Factor-1 (IGF-1) SignalingC ascad

Anterior Gradient-2 (AGR2) protein is differentially expressed in many tumor cells and itcan be both cytoplasmic and secreted.AGR2 promotes tumor formation, anchorage independentgrowth, migration and metastasis of tumor cells.