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Fifty-six male Sprague-Dawley rats were randomly assigned to 7 groups: Control group, sham-operated group, VC group,three polysaccharide-treated VC groups (25 mg/kg.d, 50 mg/kg.d, 100 mg/kg.d respectively), and saline-treated VC group.Experimental varicocele was induced by partial ligation of the left renal vein.