Molecular Biomarkers of Pancreatic Intraepithelial Neoplasia and Their Implications in Early Diagnos

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：zx20060522

【摘要】

：

Lack of early detection and effective interventions is a major reason for the poor prognosis and dismal survival rates for pancreatic cancer.

【作者】

：

Junli GUO Keping XIE Shaojiang Zheng

【机构】

：

Department of Pathology,Affiliated Hospital of Hainan Medical College,Hainan Cancer Hospital,Hainan

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

PanINs Biomarker Early Diagnosis Therapeutic Intervention

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Lack of early detection and effective interventions is a major reason for the poor prognosis and dismal survival rates for pancreatic cancer.

其他文献

Upregulation of Id3 inhibits cell proliferation and induces apoptosis in A549/DDP human lung cancer

Objectives:Lung cancer is the leading cause of cancer-related mortality worldwide.Id3 is a member of the Id multigene family of dominant negative helix-loop-helix transcription factors,which functions

会议

Id3A549/DDPproliferationapoptosis

血清Tg与内源性TgAb浓度的对分化型甲状腺癌术后复发/转移的诊断价值

目的：评价甲状腺组织完全去除后血清甲状腺球蛋白(TG)与抗甲状腺球蛋白抗体(TGAb)对分化型甲状腺癌(DTC)的诊断价值。方法：选择225例术后病理诊断为DTC,残留甲状腺组织已完全去除的患者,将其分为：复发/转移组(A组)82例和无复发/转移组(B组)143例。以电化学发光法测定血清TG、TGAb水平,根据其TG、TGAb值进行受试者丁作特征(ROC)曲线及不同阈值的阳性分层似然比分析。

会议

分化型甲状腺癌甲状腺球蛋白甲状腺球蛋白抗体

Pimozide联合CpG ODN促进结肠癌荷瘤小鼠的抗肿瘤作用

研究背景及目的：CpG ODN已经被广泛的证明具有抗肿瘤作用.YW002作为一种C型CpG ODN业已经被证明具有一定的肿瘤作用.然而,目前单一疗法都无法真正的治愈肿瘤病人,联合治疗已经成为一种研究热点.研究表明,STAT5在结肠癌病人中呈现一种高表达状态,其已经成为了肿瘤靶点治疗的一个热点.

会议

PimozideCpG ODN结肠癌

Knockdown of PDZ-binding kinase in triple negative breast cancer cells decreases their invasiveness

Objective: To investigate the role of PDZ-binding kinase (PBK) (also named T-lymphokine activated killer cell originated protein kinase (TOPK)) in cell migration and invasion.

会议

PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK)triple-negati

Prognostic impact of tumor associated macrophages in patients with Urothelial Cell Carcinoma of the

Backgroud and Purpose: Inflammation responses are involved in bacillus Calmette-Guerin (BCG) immunotherapy of Urothelial Cell Carcinoma of the Bladder (UCB).

会议

bladder cancerimmunohistochemistryprognosismacrophages

Placenta polypeptide promote PP regimen's curative effects on advanced lung adenocarcinoma thro

Objective: To study placenta polypeptides promotion on PP regimens curative effects on Ⅲ, Ⅳ staging lung adenocarcinoma through regulating T lymphocyte.

会议

Lung cancerPlacenta polypeptidePPImmunityQuality of life

靶向双抗原至B细胞增强抗肿瘤免疫应答的机制研究

目的：B细胞不但具有抗体产生功能，也是潜在的抗原递呈细胞。我们前期研究发现通过CD19分子单链抗体(single chain variable fragment：scFv)将单个肿瘤抗原靶向至B细胞，能增强宿主的体液免疫和细胞免疫应答，但如何维持长久有效的抗肿瘤免疫应答则需进一步深入研究。

会议

B细胞CD19单链抗体肿瘤免疫

食管鳞癌肿瘤引流淋巴结中IDO及其相关抑癌基因Bin1的表达情况的研究

目的：研究食管鳞癌患者肿瘤引流淋巴结(tumor draining lymph node,TDLN) IDO和Bin1基因的表达情况,探讨TDLN内IDO和Bin1基因表达状态的改变在食管鳞癌进展中的意义。方法：收集2013年4月至2014年3月在河北医科大学第四医院胸外科行肿瘤切除并经病理证实的食管鳞癌患者的TDLN样本,使用RT-PCR检测IDO和Bin1 mRNA的表达情况,分析二者表达的相

会议

食管鳞癌肿瘤引流淋巴结IDO mRNABin1 mRNA

The NEDD8-activating enzyme inhibitor MLN4924 induces G2 arrest and apoptosis of T-cell acute lympho

The first in class compound MLN4924 is a small molecule inhibitor that selectively inactivates NEDD8-activating enzyme (NAE).

会议

neddylationMLN492T-ALLG2 arrestapoptosisribosomal protein

Significance of CA125 combined with ratio of neutrophil to lymphocyte in the diagnosis and prognosis

Objective: To evaluate the sensitivity and specificity of CA125 combined with ratio of neutrophil to lymphocyte in the diagnosis and prognosis of ovarian cancer.The significance is to find a new marke

会议

Ovarian CancerTumor MarkersCA125Ratio of Neutrophil to Lymphocyte

Molecular Biomarkers of Pancreatic Intraepithelial Neoplasia and Their Implications in Early Diagnos

其他学术论文