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Graphene-based materials have attracted considerableinterest on grounds of their novel characteristics,such as largespecific surface area,high thermal and mechanical properties.Additionally,metallic nanoparticles are found to present excellentelectrocatalytic performance and notable electrical conductivity,providingbetter electrochemical response(higher current response) to thesensor,making them a considerably ideal material for the preparationof chemical and biological sensors.Graphene and it scomposites are suitablefor modifying electrochemicalbiosensors.