伯氏疏螺旋体膜蛋白BmpA研究进展

来源 :第四届中国临床微生物学大会暨微生物学与免疫学论坛 | 被引量 : 0次 | 上传用户:dantezb
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  莱姆病是一种人兽共患病,已严重威胁人类健康,成全球公共卫生问题,引起全球关注.伯氏疏螺旋体是通过蜱叮咬传播而引起人莱姆病的病原体,其表面存在众多膜蛋白,具有免疫性和致病性.BmpA (Borrelia Burgdorferi membrance proteinA)是伯氏疏螺旋体的主要抗原,为层粘连蛋白结合蛋白,是莱姆关节炎的致病因子.本文就BmpA在蛋白功能,诊断应用和莱姆关节炎致病机理三方面研究进展作一综述.
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