【摘 要】
:
莱姆病是一种人兽共患病,已严重威胁人类健康,成全球公共卫生问题,引起全球关注.伯氏疏螺旋体是通过蜱叮咬传播而引起人莱姆病的病原体,其表面存在众多膜蛋白,具有免疫性和致病性.BmpA (Borrelia Burgdorferi membrance proteinA)是伯氏疏螺旋体的主要抗原,为层粘连蛋白结合蛋白,是莱姆关节炎的致病因子.本文就BmpA在蛋白功能,诊断应用和莱姆关节炎致病机理三方面研究
【机 构】
:
昆明医学院 中国云南昆明 650500 昆明市疾控中心 中国云南昆明 650034
【出 处】
:
第四届中国临床微生物学大会暨微生物学与免疫学论坛
论文部分内容阅读
莱姆病是一种人兽共患病,已严重威胁人类健康,成全球公共卫生问题,引起全球关注.伯氏疏螺旋体是通过蜱叮咬传播而引起人莱姆病的病原体,其表面存在众多膜蛋白,具有免疫性和致病性.BmpA (Borrelia Burgdorferi membrance proteinA)是伯氏疏螺旋体的主要抗原,为层粘连蛋白结合蛋白,是莱姆关节炎的致病因子.本文就BmpA在蛋白功能,诊断应用和莱姆关节炎致病机理三方面研究进展作一综述.
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