Transient Trapping in Enantioseparation for High-Sensitive Detection.3

• 作 者: HiroshiKoino[1]KenjiSueyoshi[2]FumihikoKitagawa;KojiOtsuka;
• 机 构: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510,
• 出 处: 第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会
• 发表日期: 2011年期

　　Cyclodextrin electrokinetic chromatography (CDEKC) is one of the versatile methods for the enantioseparation in capillary electrophoresis.CDEKC has great advantages such as the rapid separation, high resolution and low consumption of samples/reagents, while a low concentration sensitivity due to a short optical path length is often problematic.To improve the sensitivity, various on-line and off-line preconcentration techniques have been applied to CDEKC [1].In this study, a novel on-line sample preconcentration technique named transient trapping (tr-trapping) [2] was combined with CDEKC to achieve a rapid and highly sensitive enantioseparation.