Nucleoprotein but not Phosphoprotein of Human Parainfluenza Virus Type 3 interaction with Matrix pro

来源 :第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 | 被引量 : 0次 | 上传用户：baronsong2009

【摘要】

：

【作者】

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Guangyuan Zhang Yi Zhong Yali Qin Mingzhou Chen

【机构】

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State Key Laboratory of Virology and Modem Virology Research Center,College of Life Sciences,Wuhan U

【出处】

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第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会

【发表日期】

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2015年6期

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Human Parainfluenza virus type 3 (HPIV3) belongs to the Paramyxoviridae family.Its three internal viral proteins,the nucleoprotein (N),the phosphoprotein (P),and the polymerase (L),form the ribonucleoprotein (RNP) complex,which encapsidates the viral genome and associates with M protein for virion assembly.We previously showed that the M protein expressed alone is sufficient to assemble and release virus-like particles (VLPs),and a point mutant of M protein,ML305A,has a VLP formation ability similar to that of wild-type M protein.

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Nucleoprotein but not Phosphoprotein of Human Parainfluenza Virus Type 3 interaction with Matrix pro

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