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  5. Inhibitory effect of ginsenoside Re on neointimal hyperplasia of carotid artery in balloon-injured r

Inhibitory effect of ginsenoside Re on neointimal hyperplasia of carotid artery in balloon-injured r

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：liangzhenghai
【摘 要】
：
Aim: To examine the effects of ginsenoside Re (Re) on neointimal hyperplasia of carotid artery in balloon-injured rats and explore relevant mechanisms.Methods: Balloon-injured carotidartery models was
【作 者】
：
Yang GAO Jie YANG Jiang DENG Dan-li YANG 
【机 构】
：
Department of pharmacology,The key laboratory of basical phamrcology of Guizhou province,Zunyi Medic
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
Re balloon-injury pERK1/2 MKP-1 
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Aim: To examine the effects of ginsenoside Re (Re) on neointimal hyperplasia of carotid artery in balloon-injured rats and explore relevant mechanisms.Methods: Balloon-injured carotidartery models was established.Animals were then injected (ip) with normal saline or Re in the model, sham operation (injected with distilled water), and Ginsenoside Re-low groups (Re 6 mg/kg/d), Ginsenoside Re-moderate groups (Re 12 mg/kg/d), ginsenoside Re-high groups (Re 24 mg/kg/d), respectively.
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