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Well-defined amphiphilic graft copolymers,hydroxypropycellulose graft poly(2-acryloyloxyethyl ferrocenecarboxylate) (HPC-g-PAEFC),were synthesized via atom transfer radical polymerization (ATRP) (Scheme 1).The self-assembly and redox- and thermo-responsive properties of the obtained HPC-g-PAEFC copolymers in aqueous solutions were investigated by dynamic light scattering (DLS),transmission electron microscopy (TEM),and transmittance.