Parkinsons disease(PD)is a neurodegenerative disease characterized by a movement disorder,including tremor,rigidity,bradykinesia,and postural instability,resulting from the degeneration of dopaminergi
Parkinsons disease(PD)pathology is characterized by the formation of intra-neuronal inclusions called Lewy bodies,which are comprised of alpha-synuclein(α-syn).
Objective To study the molecular mechanism of abnormal glutamate transporter expression and function in Parkinsons disease(PD)and find new targets for treating PD.
Parkinsons disease(PD)is a central nervous system degenerative disease,which is based on the degeneration of nigrostriatal dopaminergic neurons and the decrease of dopamine in striatum.
Objective To investigate the relationship between TLR3-TRIF signaling pathway and microglial activation as well as polarization of distinct microglia M1/M2 phenotypes,and the effect of microglia condi