A miR-573/apoM/Bcl2A1-dependent Signal Transduction Pathway Is Essential for Hepatocyte Apoptosis an

• 作 者: Jia-YiZhao;Yan-WeiHu;Shu-FenLi;Xiu-MeiHu;Ya-RongHu;Jin-LanHuang;LeiZheng;QianWang;
• 机 构: Laboratory Medicine Center,Nanfang Hospital,Southern Medical University,Guangzhou,Guangdong 510515,C
• 出 处: 第七届粤桂琼检验医学新进展学术大会
• 发表日期: 2013年期

　　Hepatocellular carcinoma (HCC) is one of the most common malignant tumors and its incidence has been increasing worldwide.Apolipoprotein M (apoM) is a novel apolipoprotein and is mainly expressed by liver and kidney tissues.However,anti-tumor properties of apoM are seldomly addressed.In the present study,we evaluated the anti-tumor activity and mechanisms of apoM on HCC in vivo and in vitro.