This study intended to fabricate phenazopyridine/phthalimide (PAP/PIMD) nano-cocrystal to improve dissolution and oral bioavailability.PAP/PIMD nano-cocrystal is prepared by sonochemical synthesis,usi
Pharmaceutical cocrystallization is proposed as a new method to enhance membrane permeability of a BCS class Ⅲ model drug,5-fluorouracil (5FU).Three cocrystals of 5FU,5FU/3-hydroxybenzoic acid (1),5FU
we described a Rivaroxaban (RIV) nanocrystal for overcoming poor solubility here.The results showed that using dissocubes method with polxamer 188、 Hydroxy Propyl Methyl Cellulose (HPMC) E9 and Sodium
Dapagliflozin (DAP) is a potent and selective sodium-glucose contransporter-2 (SGLT-2) inhibitor,and performed as an efficacious treatment for type 2 diabetes.Sever hygroscopicity of DAP hinder the us
Linezolid (LZD) is one of the first commercially available synthetic oxazolidinone antibiotics and is widely used for the treatment of multidrug-resistant Gram-positive bacterial infection.LZD was fou