Crystal structure of a GH39 β-xylosidase CmXynB1 from a deep-sea bacterium Croceicoccus marinus E4A9

来源 :中国生物化学与分子生物学会2016年全国学术会议 | 被引量 : 0次 | 上传用户:pkpm1
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  β-xylosidases are glycosidase hydrolases that hydrolyze short xylooligosaccharides into xylose units,which contribute to the final breakdown of plant cell-wall hemicelluloses.Here,we determined the three-dimensional structure of a GH39 β-xylosidases CmXynB1 from a marine bacterium Croceicoccus marinus,which is isolated from the East Pacific polymetallic nodule region.The CmXynB1 showed low second structural identity with other known xylosidases,however,shared similar catalytic fold on 3-D structure.Each monomer of CmXynB1 has a canonical(α/β)8-barrel catalytic domain and an auxiliary β-sandwich domain that plays a role in recognizing the substrate.The structure of CmXynB1 might provide new insights into understanding the mechanism-oxfy loβsidase family.
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