基于润湿特性仿生的PDMS功能涂层自图形化

来源 :第八届全国微全分析系统学术会议、第三届全国微纳尺度生物分离分析学术会议暨第五届国际微化学与微系统学术会议 | 被引量 : 0次 | 上传用户:fencer_2
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  PDMS 微流控芯片常需要各种表面改性,而已有的各种气相、液相涂层方法都难以保证涂层覆盖准确性和均匀性。受非洲沙漠甲虫及超亲水叶子的润湿特性启发,我们提出一种极为高效、便捷的PDMS 表面涂层自图形化 (self-patterning) 方法。动植物的亲水、疏水润湿特性可高效地操控液体的黏、滑行为(图a),因此,我们通过粗糙度设计润湿梯度,以蒸发为驱动力便可精确地将溶质沉积、固化在粗糙的3D 微通道上,而不会留在光滑顶面(图b)。利用氧气等离子体选择性攻击SU-8 而非Si 的特点,可便捷地把SU-8 与Si 的粗糙度复制到PDMS 上,从而使涂层蒸发后只分布在通道内,兼容PDMS-玻璃邦定(图c)。利用此方法,我们示范了疏水CYTOP 涂层在PDMS 复杂流路中的100%覆盖准确性和良好的均匀性(图d-e)。与无涂层PDMS 相比,溶胀被显著抑制,非特异性荧光染料吸附被有效消除(图f-g)。这种自图形化方法廉价、高效、快速,可广泛用于PDMS 微流控芯片使用各种功能涂层进行表面改性。
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