Effect of WuziYanzong Pill on Cox7a2 gene and Claudin-11 expression in Rats with kidney essence defi

来源 :GTAUF2014 & APSMHA2014第六届长城泌尿男科转化医学论坛暨第七届亚太男性健康与抗衰老研究学会年会 | 被引量 : 0次 | 上传用户：lwhssg

【摘要】

：

【作者】

：

Baoxing Liu

【机构】

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Department of Andrology, China-Japan Friendship Hospital, Beijing 100029, China

【出处】

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GTAUF2014 & APSMHA2014第六届长城泌尿男科转化医学论坛暨第七届亚太男性健康与抗衰老研究学会年会

【发表日期】

：

2014年11期

【关键词】

：

Cox7a2 gene Claudin-11 kidney essence deficiency syndrome

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Objective: To observe the effects of WuziYanzong Pill (WYP) on Cox7a2 gene, Claudin-11 expression and to investigate extracellular signal-regulated kinase (ERK) phosphorylation in rat with kidney essence deficiency syndrome.Methods: Five groups of Sprague-Dawley male rats (5 in each group) were given vehicle, multiglycosides of Tripterygium Wilfordii Hook f (GTW) alone (20mg/kg),or GTW followed by WYP (0.5, 1.0, or 2.0 g/kg daily) respectively for 30 days.Cox7a2 mRNA expression in testis was determined by real-time reverse transcriptase polymerase chain reaction.The extracellular signal-regulated kinase1/2 (ERK1/2) phosphorylation level and Claudin-11 expression were assessed by western blot analysis.

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Effect of WuziYanzong Pill on Cox7a2 gene and Claudin-11 expression in Rats with kidney essence defi

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