The efficacy and safety of a steroid-free immunosuppressive regimen after liver transplantation for

• 作 者: QiangWei;YanShen;WeilinWang;ShusenZheng;XiaoXu;ChaoWang;RunzhouZhuang;LiZhuang;LinZhou;HaiyangXie;JianWu;MinZhang;
• 机 构: Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital,Z
• 出 处: 2015浙江省肿瘤外科学术年会暨首届钱江国际肿瘤外科高峰论坛
• 发表日期: 2015年期

　　Background/Aims We aimed to evaluate the efficacy and safety of an immunosuppressive regimen without steroids in liver transplantation (LT) for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC).Methods Sixty-six HCC patients underwent an immunosuppressive regimen without steroids after LT were enrolled in steroid-free group.Their preoperative characteristics and postoperative outcomes were compared with those of 132 HCC recipients (1∶2 matched) with an immunosuppressive regimen using steroids (steroid group).The incidence of acute rejection, HBV recurrence, infection, new-onset diabetes mellitus (NODM), overall and tumor-free survival rates and liver and kidney function were compared.