半相合异基因外周造血干细胞输注联合化疗治疗血液系统恶性疾病17例报道

来源 :中华医学会血液学分会第九次全国造血干细胞移植学术会议 | 被引量 : 0次 | 上传用户：carole_369

【摘要】

：

目的观察G-CSF动员的半相合异基因外周造血干细胞输注联合化疗治疗恶性血液病的安全性.方法 17例恶性血液病患者在化疗结束24-48h内给予半相合异基因外周造血干细胞输注,共3疗程;12例急性髓系白血病患者,5例骨髓增生异常综合症患者;17例均为亲缘关系供者,其中12对供受者3个位点相合,5对为4个位点相合.

【作者】

：

李坦刘媛媛李斌牛伶鲍扬漪

【机构】

：

合肥市第一人医院血液肿瘤科 230031

【出处】

：

中华医学会血液学分会第九次全国造血干细胞移植学术会议

【发表日期】

：

2015年4期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Notch1信号通路对异基因造血干细胞移植后损伤肝细胞的修复作用研究

目的探讨Notch1信号通路对异基因造血干细胞移植(HSCT)后损伤肝细胞的修复作用.方法将小鼠经致死剂量全身照射(TBI)后随机分为单纯照射预处理组及异基因造血干细胞移植组,正常小鼠为对照组.

会议

De novo-generated donor-derived CD4+ T cells in recipients given low dose donor CD8+ T cells play an

目的 To invest the function of CD4+ T cells and CD8+ T cells in cGVHD.方法 1.Lethally irradiated BALB/c recipients were transplanted with donor C57BL/6 TBCD-BM (2.5 × 106) and 0.1 ×106donor CD4+ or CD8+ T

会议

Reprogramming adult mesenchymal stem cells into functional hematopoietic stem cells used for the tre

目的 Naturally-occurring regeneration of cells and tissues is generally involved in four working mechanisms such as directed differentiation, dedifferentiation, trans-differentiation and transdeterminat

会议

Induction of autophagy by valproic acid enhanced lymphoma cell chemo-sensitivity through an HDAC-ind

目的 Despite a remarkable progress in lymphoma treatment over the past decades, chemotherapy resistance and disease relapse become the main obstacles to further improve the prognosis of the patients.Ind

会议

miR-153-3p, a new bio-target, is involved in the pathogenesis of acute graft-versus-host disease thr

目的 In the current, many studies investigating acute graft-versus-host disease (aGVHD) after hematopoietic stem cell transplantation (HSCT) have focused on seeking potential biomarkers to predict its o

会议

异基因移植中输注内皮祖细胞对移植后细胞因子释放的作用研究

目的研究内皮祖细胞(EPC)对异基因移植后细胞因子释放的作用影响.方法以C57BL/6小鼠为供鼠,BABL/C小鼠为受鼠并将其随机分为3组,即对照组:正常小鼠、单纯骨髓移植组;实验组:骨髓联合EPC移植组,于移植后2、4、6、8、10天利用流式细胞术,CBA法检测BABL/C小鼠血清中IL-6、IL-10、MCP1、IFN-γ、TNF-α、IL-12p70的水平.

会议

Foxm1 is essential for quiescence and maintenance of hematopoietic stem cell

目的 Tight regulation of the cell cycle in hematopoietic stem cells (HSCs) is essential for maintaining their lifelong self-renewal capacity.

会议

PDGFR-mediated cytomegalovirus infection of megakaryocytes induces thrombocytopenia via demethylatio

目的 Human cytomegalovirus (HCMV) infection is a common complication of allo-hematopoietic stem cell transplantation (allo-HSCT), which is associated with high morbidity and mortality.

会议

Fhl2 regulates the function of hematopoietic stem/progenitor cells

目的 FHL2, a member of the four and one half LIM domain protein family, is a critical transcriptionalmodulator.

会议

Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Th

目的 Prolonged isolated thrombocytopenia (PIT) represents a significant complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and is associated with an adverse patient progn

会议

半相合异基因外周造血干细胞输注联合化疗治疗血液系统恶性疾病17例报道

其他学术论文