Two-stage induced differentiation of OCT4+/Nanog+ stem-like cells in lung adenocarcinoma

来源 :第十八届全国临床肿瘤学大会暨2015年CSCO学术年会 | 被引量 : 0次 | 上传用户：wy2633110

【摘要】

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Objective: Stem-like cells in solid tumors are purported to contribute to cancer development and poor treatment outcome.The abilities to self-renew, differentiate, and resist anticancer therapies are

【作者】

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Rong Li Jinsu Huang Meili Ma Yuqing Lou Yanwei Zhang Lixia Wu David w.Chang Picheng Zhao Qianggang Dong Xifeng Wu Baohui Han

【机构】

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Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University

【出处】

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第十八届全国临床肿瘤学大会暨2015年CSCO学术年会

【发表日期】

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2015年4期

【关键词】

：

lung cancer stem cell vitamin D

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　　Objective: Stem-like cells in solid tumors are purported to contribute to cancer development and poor treatment outcome.The abilities to self-renew, differentiate, and resist anticancer therapies are hallmarks of these rare cells, and steering them into lineage commitment may be one strategy to curb cancer development or progression.

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Two-stage induced differentiation of OCT4+/Nanog+ stem-like cells in lung adenocarcinoma

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