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Salvia miltorrhiza Bunge is a traditional Chinese medicine and has long been used for treating liver and heart diseases in China.Salvianic acid A (SAA) is the main hydrophilic active component of Salvia miltorrhiza Bunge.The radioprotective effect of SAA against γ-ray radiation-induced apoptosis and its possible protective mechanisms were investigated.SAA was found to recover the cell viability damaged by radiation via the inhibition of apoptosis.