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  5. Gecko Peptides Mixture induce apoptosis in human esophageal squamous carcinoma EC109 cell line in vi

Gecko Peptides Mixture induce apoptosis in human esophageal squamous carcinoma EC109 cell line in vi

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：yaoyaoqi
【摘 要】
：
Aims: To investigate the effect of Gecko Peptides Mixture (GPM) on apoptosis of human esophageal squamous carcinoma EC109 cell line and the molecular mechanisms.Methods: EC109 cells were cultured in v
【作 者】
：
Xin-li XU Jian-gang WANG Rui-fang LI Leng-xin DUAN Chao-chu CUI Wan-li ZHANG 
【机 构】
：
The Key laboratory of Pharmacology and Medical Molecular Biology,Medical College,Henan University of
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
gecko peptides mixture human esophageal squamous carcinoma apoptosis Bcl-2 caspa 
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Aims: To investigate the effect of Gecko Peptides Mixture (GPM) on apoptosis of human esophageal squamous carcinoma EC109 cell line and the molecular mechanisms.Methods: EC109 cells were cultured in vitro and the inhibitory effect of GPM on their proliferation was measured by MTT assay.The apoptosis of EC109 cells was determined by Hoechst 33258 fluorescence staining.The effects of GPM on Bcl-2 and caspase-3 protein expression of EC109 cells were investigated by using immunohistochemical method.
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