In vitro activity of ceftazidime-avibactam and aztreonam avibactam against 372 Gram-negative bacilli

• 作 者: XiaojuanWang[1]FeifeiZhang[1]ChunjiangZhao[1]ZhanweiWang[1]WrightW.Nichols[2]RaymondTesta[2]HenanLi[1]HongbinChen[1]WenqiangHe[1]QiWang[1]HuiWang[1]
• 机 构: Department of Clinical Laboratory, Peking University People's Hospital, Beijing, 100044, China
• 出 处: 第二届京港感染医师论坛
• 发表日期: 2013年期

　　Background: Avibactam is a member of a class of inhibitors called diazabicyclooctanes (DBOs) that does not contain a β-lactam core but maintains the capacity to covalently acylate its β-lactamase targets.This study aims to determine in-vitro activity of ceftazidime-avibactam and aztreonam-avibactam against gram-negative bacilli including different β-lactamases-producers from 11 teaching hospitals in China.