SURFACEOME ANALYSIS OF HUMAN PLURIPOTENT STEM CELL DERIVED CARDIOMYOCYTES

来源 :19th Annual Scientific Meeting of the Institute of Cardiovas | 被引量 : 0次 | 上传用户：yl198710310318

【摘要】

：

【作者】

：

E Poon RL Gundry KR Boheler

【机构】

：

Stem Cell and Regenerative Medicine Consortium;School of Biomedical Sciences,LKS Faculty of Medicine

【出处】

：

19th Annual Scientific Meeting of the Institute of Cardiovas

【发表日期】

：

2015年9期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Objectives: Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) are highly heterogeneous and show a variety of chamber types (ventricular, atrial and pacemaker) and maturation states.Immunophenotyping and isolation of homogeneous subpopulations using antibodies against surface proteins would be critical for the use of hPSC-CMs for drug screening and transplantation.Our aim is to characterize the suffaceome of hPSC-CMs.

其他文献

TETRAMETHYLPYRAZINE REGULATES SOLUBLE EPOXIDE EXPRESSION IN CORONARY ENDOTHELIUM:ANTI-ER STRESS AGAI

Objectives: Tetramethylpyrazine (TMP), an active ingredient of Chinese herb Chuanxiong, is known for cardioprotective benefits due to its anti-oxidant and anti-inflammatory properties.

会议

CONDITIONAL KNOCKOUT OF FGF13 IN MURINE HEARTS CAUSES FLECAINIDE-INDUCIBLE VENTRICULAR TACHYARRHYTHM

Aims: Cardiac Na+ channels play critical roles in impulse generation and conduction in ventricular tissue.Fibroblast growth factor homologous factors (FHFs) are essential modulators of Na+ channels an

会议

MACROPHAGE MIGRATION INHIBITORY FACTOR PROMOTES EXPRESSION OF GLUT4 GLUCOSE TRANSPORTER THROUGH MEF2

Objective: Evidence shows that both macrophage migration inhibitory factor (MIF) and GLUT4 glucose transporter are involved in diabetic cardiomyopathy (DCM), but it remains largely unknown whether and

会议

CHOLINERGIC STIMULATION WITH PYRIDOSTIGMINE EXERTS PROTECTIVE EFFECTS IN RAT MODELS OF CARDIAC REMOD

Background: Cardiac remodeling in cardiovascular diseases is always accompanied by enhanced sympathetic activity and withdrawal of parasympathetic control.Recent studies showed that vagal nerve stimul

会议

TARGETED INHIBITION OF ATP-BINDING CASSETTE TRANSPORTER A1 PROTEIN DEGRADATION PROMOTES REVERSE CHOL

ABCA1 is a 2,261-amino-acid integral membrane protein that comprises two halves of similar structure.Each half has a transmembranc domain containing six helices and a nucleotide binding domain (NBD) c

会议

LIPOPROTEIN (A) IS A RISK FACTOR FOR CORONARY ARTERY DISEASE IN CHINESE HAN ETHNIC POPULATION MODIFI

Background: Lipoprotein (a) (Lp (a)) is a well-established risk factor for coronary artery disease (CAD) in Caucasians.However, data regarding the association of Lp (a) with CAD are lacking in Chinese

会议

UPCONVERSION NANOPARTICLE-MEDIATED PHOTODYNAMIC THERAPY INDUCES THP-1 MACROPHAGE APOPTOSIS THROUGH T

Objectives: Atherosclerosis (AS) is the most vital cardiovascular disease,which poses a great threat to human health.Macrophages play an important role in the progression of AS.Photodynamic therapy (P

会议

MICRORNA-133B REGULATES PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS INDUCED BY LOW SHEAR STRESS

Objectives: Shear stress, especially low shear stress (LowSS), plays a crucial role in vascular remodeling, which is a major component of many cardiovascular diseases.Our previous study revealed that

会议

MINOCYCLINE-SUPPRESSED PERIPHERAL INFLAMMATION IS ASSOCIATED WITH HYPOXIA-INDUCED NEONATAL BRAIN INJ

Objective: While extensive studies report that neonatal hypoxia-ischemia (HI) induces long-term cognitive impairment via inflammatory responses in the brain, little is known about the role of leukocyt

会议

GENOME-WIDE ASSOCIATION STUDY OF ESSENTIAL HYPERTENSION IN CHINESE TIBETAN POPULATION

Essential hypertension (EH) is a complex trait disease, resulting from the interaction of genetic and environmental factors.In China, there is a significant difference of EH incidence and prevalence a

会议

SURFACEOME ANALYSIS OF HUMAN PLURIPOTENT STEM CELL DERIVED CARDIOMYOCYTES

其他学术论文