Posttranslational modification of proteins by ubiquitin (Ub) plays an important role in diverse cellular events,including cell division,differentiation,signal transduction and protein trafficking.Affi
We used a systems biology approach to identify and score protein interaction subnetworks and plasma biomarkers whose activity patterns are discriminative of cervical squamous cell carcinoma (CSCC) ver
Pre-eclampsia (PE) is a pregnancy-specific disease that complicates 2-8% of all pregnancies and is associated with serious perinatal and maternal morbidity and mortality.
The complex branching and isomeric nature of glycans pose significant challenges to the characterization of these structures.The recently developed GlycanPac AXH-1 columns are specifically designed fo
The average duty cycle of Time of Flight analysers is dependant on the m/z data acquisition range but the integration of travelling wave ion mobility devices in QToF geometries can afford significant
Small changes in the proteome can have dramatic biological effects.Detecting these changes amid a background of abundant housekeeping and structural proteins can be challenging.Proving statistical sig
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is an indispensable method in oligosaccharide analysis.The choice of matrix,which realizing the ionization o
Biological samples from patients are invaluable for both medical research and medical practice.Ideally,the samples should be preserved for the same period of time as the duration of their correspondin