Distribution and expression in vitro and in vivo of DNA vaccine against lymphocystis disease virus i

• 作 者: FengrongZheng[1]XiuqinSun[1]HongzhanLiu[2]XinganWu[3]NanZhong[3]BoWang[1]GuodongZhou[4]
• 机 构: First Institute of Oceanography SOA, Qingdao, 266061
• 出 处: 第一届全国鲆鲽类产业可持续发展研讨会
• 发表日期: 2010年期

　　Lymphocystis disease,caused by the lymphocystis disease virus (LCDV),is a significant worldwide problem in fish industry causing substantial economic losses.In this study,we aimed to develop the DNA vaccine against LCDV,using DNA vaccination technology.We evaluated plasmid pEGFP-N2-LCDV1.3 kb as a DNA vaccine candidate.