The bio-function analysis on rm-ZH the Novel regulator of secondary metabolism and morphogenesis in

• 作 者: Zhenhong Zhuang Yu Li Xinyi Nie Bin Wang Feng Zhang Shihua Wang
• 机 构: Key Laboratory of Pathogenic Fungi and Mycotoxins of Fujian Province,and School of Life Sciences,Fuj
• 出 处: 2015第八届中国模式真菌研讨会
• 发表日期: 2015年3期
• 关键词: RM-ZH Aspergillus flavus morphological differentiation secondary metabolis

　　Secondary metabolism and morphological differentiation in the model fungus Aspergillus nidulans and A.flavus is controlled by the conserved global regulator VeA.The presence of VeA is necessary for the biosynthesis of sterigmatocystin(ST),a carcinogenic compound,which is the penultimate precursor of aflatoxin(AF).A revertant mutant(RM)able to synthesize ST intermediates in the absence of VeA in A.nidulans was identified.