【摘 要】
：
Superior to free gold nanoparticles(Au NPs)/silver nanoparticle(Ag NPs)-based surface-enhanced Raman spectroscopy(SERS)substrates with relatively low enhancement factor(EF)values(e.g.,~104-5)and poor
【机 构】
：
Institute of Functional Nano & Soft Materials(FUNSOM),Soochow University,Suzhou 215123,China
【出 处】
：
2016年分析化学前沿国际研讨会及中美分析化学研讨会
论文部分内容阅读
Superior to free gold nanoparticles(Au NPs)/silver nanoparticle(Ag NPs)-based surface-enhanced Raman spectroscopy(SERS)substrates with relatively low enhancement factor(EF)values(e.g.,~104-5)and poor reproducibility,the SERS silicon chip made of Ag NPs modified silicon wafer(Ag NPs@Si)or Au NPs decorated silicon nanowire array(Au NPs@SiNWAr)display higher EF values(e.g.,~106-7)ascribed to their high-efficacy SERS hot spots efficiently coupled with semiconducting silicon substrates,significantly facilitating SERS enhancement.[1] Moreover,metal NPs can be tightly immobilized on silicon substrates,effectively avoiding the random aggregation of free Au/Ag NPs,resulting in relatively good reproducibility(e.g.,RSD<17%).[1] As a consequence,a variety of SERS silicon chips have been developed for sensitive and selective detection of various chemical and biological species(e.g.,Hg2+,Pb2+,DNA,cell and bacteria)in real systems in reliable and reproducible manners.
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