Modulation of Gut Microbiota during Probiotics-Mediated Attenuation of Metabolic Syndrome in High Fa

• 作 者: Jingjing Wang Martin Obin Jian Shen Huang Tang Chenhong Zhang Yufeng Zhao Muriel Derrien Emilie Rocher Johan ET van-Hylckama Vlieg Katherine Strissel Liping Zhao
• 机 构: Ministry of Education Key Laboratory for Systems Biomedicine, Shanghai Centre for Systems Biomedicin
• 出 处: 第四届国际人体微生态大会、第十三届中华预防医学会微生态学学术会议、第五届中国医师协会感染科医师大会暨传染病诊治高峰论坛、
• 发表日期: 2013年5期

　　Background Structural disruption of gut microbiota and associated inflammation are considered important etiological factors in high fat diet (HFD)-induced metabolic syndrome (MS).As one gut microbiota-targeted approach,probiotics have been used to attenuate high fat diet (HFD)-induced MS in rodent models,and different strains exhibit varied functional effects on MS features.However,the effects of different probiotic strains on gut microbiota composition and the relationship between these modulating effects and improvements in host metabolic health is poorly understood.