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For millions of years,cells have been thought of as Natures building blocks that make us what we are."Let the cell do the work" is a general principle guided laboratory oriented biological research.Advance in Engineering and Life Sciences today has emerged an interdisciplinary paradigm of Biofabrication in which cells and other biologics are being used as engineering and/or biological building blocks to invent novel manufacturing processes and medical as well as therapeutic products.Biofabrication encompass a wide range of engineering,physical,chemical,and biological processes with a broad application in tissue science and engineering,disease pathogeneses study,drug testing and discovery,biosensors,and cell and organ printing.