Food additive sulfite increases triglyceride content and secretion of very low density lipoprotein

来源 :环境与健康——从科研到政策国际论坛暨中国环境科学学会环境医学与健康分会2013年会 | 被引量 : 0次 | 上传用户:lj55769145
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Sulfite exposure was reported to increase minor lipid droplets numbers and accumulation of triglyceride(TG) in the hepatocytes in mice caused by inhibition of secretion of VLDL We did in vitro study to test this hypothesis.Our results suggested that sulfite inhibited carnitine palmitoyltransferase (CPT1) expression and increased TG content in hepatocytes at the same time, it suggested that sulfite may cause lipid accumulation by inhibition of fatty acid β-oxidation.
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