Mechamisms of β3GnT8 regulation in gastrointestinal cancer invasion/metastasis and drug resistance

来源 :2016年全国糖生物学学术会议 | 被引量 : 0次 | 上传用户:edwardeternity
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  Objective: In order to investigate the regulation mechamisms of β3GnT8 in gastric cancer invasion and metastasis and colon cancer drug resistance,a depth and systematic study of β3GnT8 and polylactosamine was carried out from genes to glycans and from cell inside to cell outside.
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Objectives: In order to explore the relationship between polylactosamine chains and leukemia cells SAHA-resistant and then find new therapeutic target and investigate the mechanism of Chinese medicine
Objective: To investigate the transcriptional regulation of glycosyltransferase β3GnT8 by transcription factor c-Jun and the research on transcription factor c-Jun and β3GnT8 in invasion and metastasi