Adrenergic signaling mediates pancreatic hyperalgesia through activation of purinergic receptors in

• 作 者: Hong-YanZhu;ShushengWang;YoulangZhou;ZishengLiu;ShufenHu;Hong-HongZhang;XinghongJiang;Guang-YinXu;
• 机 构: Laboratory for Translational Pain Medicine,Department of Neurobiology,Institute of Neuroscience,Sooc
• 出 处: 长三角地区神经科学论坛暨浙江省神经科学学会2014年年会
• 发表日期: 2014年期

　　Background and Aims: The mechanism of pain in chronic pancreatitis(CP)is poorly understood and its treatment remains difficult,in large part due to our lack of knowledge about the neurobiological mechanisms in nociception.The aim of this study was designed to investigate roles of norepinephrine(NE)and P2X receptor signaling pathway in the pathogenesis of pancreatic pain in a rat model of CP.