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OBJECTIVE To investigate the effect of dehydro cavidine on behavior and dopamine of striatum in rats, and explore the possible active mechanisms.METHODS Male Sprague Dawley rats, through catalepsies, stereotyped behavior induced by APO, rotational behavior induced by APO or AMP, observed blockade effect of dehydrocavidine (DHC) on DA func tion in brain of rats by HPLC with ultraviolet detection.